“The identification of genetic variants associated with risk of developing glaucoma is reported in three independent studies published online this week in Nature Genetics. These findings may lead to better diagnostic tools or therapies for glaucoma,” goes the Medical News Today post. “In one study, Zhenglin Yang and colleagues find variants near two genes, ABCA1 and PMM2, which are associated with glaucoma risk, with or without high inner eye pressure, in individuals from China and Singapore. Both genes have been previously implicated in other eye disorders, but not glaucoma. In a second study, Puya Gharahkhani and colleagues identify variants near three genes, including ABCA1, that are associated with glaucoma risk in Australians and Americans of European descent. A third study by Christopher Hammond and colleagues combines genetic data from 18 populations, including people of Asian and European descent, and also identifies ABCA1 as a risk gene for both high inner eye pressure and glaucoma. Two other genetic variants were also linked to both of these conditions in this last study.” Read more.
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