Wednesday, January 26, 2011

New Way of Fighting Infections Associated with CLs

"Researchers at National Jewish Health and the University of Texas Southwestern Medical Center have discovered a new method to fight bacterial infections associated with contact lenses," reports EurekaAlert. The site goes on to report:
The eye normally fights infections through a variety of defense mechanisms including blinking of the eyes...Contact lenses, however, inhibit the effectiveness of blinking eyelids. Thus, bacteria can adhere to the surface of the contact lens...Eye infections can be treated with antibiotics. However, it can be difficult to eliminate the bacteria on the contact lenses, especially when they form a biofilm. ...The researchers confirmed earlier findings that cellular debris from immune cells fighting the infection actually provide the raw materials for the biofilm – DNA, actin and histones. So, they used the enzyme DNAase together with negatively charged poly aspartic acid to break down the chemical bonds of these elements that support the biofilm.

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