Tuesday, June 9, 2015
'Alzheimer Protein' May Play an Important Role in Eye Health
"Amyloid precursor protein (APP), a key protein implicated in the development Alzheimer's disease, may play an important role in eye and muscle health," according to Science Digest. "In a new report published in the June 2015 issue of The FASEB Journal, scientists have discovered that when proteins that bind to the APP, called FE65 and FE65L1, are deleted, they cause cataracts and muscle weakness in mice. Additionally, this study demonstrates that the expression of laminin, a protein pivotal for the interaction between lens epithelial cells and the lens capsule, is severely altered in mice lenses missing both FE65 and FE65L1 genes. If confirmed in human studies, the FE65 and FE65L1 proteins may become a therapeutic target for cataracts, muscular dystrophy and Alzheimer's disease." Read more.